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Abstract #2772

Assessment of transplant renal artery stenosis renal function with ASL-MRI and IVIM-MRI

Songlin Guo1, Peng Wu2, HAN Lu2, Wei Xing1, and Liang Pan1
1Third Affiliated Hospital of Soochow University, Department of Radiology, Changzhou, China, Changzhou, China, 2Philips Healthcare, Shanghai, China, Shanghai, China

Synopsis

Keywords: Kidney, Perfusion

Motivation: Noninvasive assessment of renal function is necessary in transplanted renal artery stenosis (TRAS), which significantly impacts graft function and prognosis.

Goal(s): The purpose was to evaluate renal function in patients with TRAS using ASL-MRI and IVIM-MRI.

Approach: We used ASL-MRI and IVIM-MRI to evaluate renal blood flow (RBF), D, D*, and f in TRAS, and analyzed their correlation with eGFR.

Results: Renal allograft in the stenosis group displayed notably lower RBF and f, both of which were positively associated with eGFR. This research highlights the importance of noninvasive techniques like ASL-MRI and IVIM-MRI in the clinical management of TRAS.

Impact: This study demonstrates that TRAS reduces renal perfusion, thereby affecting transplanted kidney function. ASL-MRI and IVIM-MRI can indirectly and noninvasive reflect renal function impacted by TRAS, providing valuable information for treatment decisions and active monitoring.

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Keywords