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Abstract #2813

Self-supervised variational manifold learning: application to dynamic MRI of airway collapse in obstructive sleep apnea.

Wahidul Alam1, Rushdi Zahid Rusho1, Junjie Liu2, Douglas Van Daele3, Mathews Jacob4, and Sajan Goud Lingala1,5
1Roy J. Carver Department of Biomedical Engineering, The University of Iowa, iowa city, IA, United States, 2Department of Neurology, The University of Iowa, iowa city, IA, United States, 3Department of Otolaryngology, The University of Iowa, iowa city, IA, United States, 4Department of Electrical and Computer Engineering, The University of Iowa, iowa city, IA, United States, 5Department of Radiology, University of Iowa, iowa city, IA, United States

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Machine Learning/Artificial Intelligence

Motivation: Recent manifold-based models use unsupervised generative Variational smoothness regularization on manifold framework for improved recovery. This unsupervised method lacks a well-defined automated early stopping criterion and rely on subjective qualitative assessment only.

Goal(s): We aim to adapt a physics-guided early stopping criterion to V-SToRM framework leveraging non-cartesian multi-slice acquisition.

Approach: We developed a self-supervised variational manifold recovery method where we modified the original variational manifold scheme to integrate an early stopping criterion.

Results: With early-stopping criterion enforced, we observe a faithful reconstruction of spatiotemporal dynamics at epoch 45 and images without blocky/noise amplification artifacts at different temporal phases with suppressed temporal blurring artifacts.

Impact: While preserving the integrity of the ongoing joint learning of latent variables and generator weights, the adoption of early-stopping strategy in this context streamlines the computational complexity and consequently, rendering faithful and reproducible faster reconstructions.

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Keywords