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Abstract #2814

A Comprehensive Quality Assessment on AI-assisted Fast MRI Acquisition for China Baby Connectome Project (CBCP)

Lixuan Zhu1, Zhuoyang Gu1, Xinyi Cai1, Tianli Tao1, Qing Yang1, Mingwen Yang2, Zuozhen Lan2, Lin Zhang2, Ying Lin2, Yajuan Zhang1, Jiawei Huang1, Weijun Zhang3, Jungang Liu2, Dinggang Shen1,4,5, and Han Zhang1,5
1School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, 2Department of Radiology, Xiamen Children's Hospital, Children's Hospital of Fudan University at Xiamen, Xiamen, China, 3Shanghai United Imaging Healthcare Co., Ltd., Shanghai, China, 4Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China, 5Shanghai Clinical Research and Trial Center, Shanghai, China

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Data Acquisition, MRI Acceleration, Fast Acquisition, New MRI Techniques

Motivation: Acquiring a high-quality 3D brain MRI in a short time is highly desired for infants/children studies.

Goal(s): To optimize and systemically evaluate an innovative technology, AI-assisted Compressed Sensing (ACS), used in Chinese Baby Connectome Project (CBCP) with faster 3D-T1w scans and preserved imaging fidelity.

Approach: We compared ACS with conventional techniques along the entire processing pipeline. CBCP-ACS was also compared with the existing infant cohort (BCP) with P2 acceleration regarding the derived development trajectories.

Results: Results suggested that CBCP data, with halved acquisition time, had comparable quality and derived neuroscience findings to BCP, indicating that a large cohort study with ACS is mature.

Impact: Equip high-resolution 3D-T1w MRI acquisition with ACS effectively shortens the acquisition time by 44%, providing a stable and robust solution for building large-scale infant/children brain imaging cohorts. The established technique could also facilitate clinical scans and patient studies.

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