Keywords: DWI/DTI/DKI, Diffusion Tensor Imaging
Motivation: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) is a serious sleep disorder linked to cognitive impairment. This study investigates the glymphatic system's role in OSAHS and its impact on cognition.
Goal(s): Explore glymphatic system changes in OSAHS and their influence on cognitive function. We aim to uncover the mechanisms connecting OSAHS and cognitive issues.
Approach: We use DTI-ALPS and rs-fMRI to assess the glymphatic system and brain network properties. Correlations and mediation analysis examine the link between glymphatic function, cognitive abilities, and OSAHS severity.
Results: OSAHS patients exhibit reduced glymphatic function, affecting cognitive performance.
Impact: This study may enhance comprehension of cognitive problems in OSAHS, suggesting dementia risk. It could inform early intervention, enhancing OSAHS patients' quality of life.
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