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Abstract #2884

Value of intravoxel incoherent motion diffusion-weighted MRI in evaluating endometrial receptivity in women with polycystic ovary syndrome

Wenhui Shao1, Yuwei Cao1, Feifei Qu2, Feiyun Wu1, and Ting Chen1
1The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, China, 2MR Research Collaboration, Siemens Healthineers, Shanghai, China

Synopsis

Keywords: IVIM, Reproductive, polycystic ovary syndrome, vessels, hormonal levels

Motivation: This study evaluated endometrial receptivity in women with polycystic ovary syndrome (PCOS) impacting embryo implantation and pregnancy outcomes.

Goal(s): The primary objectives were to evaluate endometrial receptivity by measuring uterine junctional zone (UJZ) and myometrium parameters and to explore the correlation between these imaging parameters and hormonal levels.

Approach: Using intravoxel incoherent motion (IVIM), the study measured the quantitative parameters of the UJZ and myometrium in women with PCOS.

Results: Patients with PCOS had lower UJZ and myometrium f values than controls, indicating reduced perfusion affecting embryo implantation. A positive correlation with free thyroxine levels was observed.

Impact: Intravoxel incoherent motion imaging is vital in assessing endometrial receptivity. Patients with polycystic ovary syndrome had lower f values of the uterine junctional zone and myometrium than controls, suggesting less blood perfusion, which might be associated with poor pregnancy outcomes.

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