Abstract #2918

Pulmonary functional imaging for patients with obstructive lung disease using UTE MRI

Li Fan¹, Jie Li^1,2, Yi Xia¹, Pu-Yeh Wu³, Meiling Xu¹, Guangyuan Sun⁴, and Shiyuan Liu¹

¹Department of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, China, ²College of Health Sciences and Engineering, University of Shanghai for Science and Technology, Shanghai, China, ³GE Healthcare, Beijing, China, ⁴Department of Thoracic Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai, China

Synopsis

Keywords: Lung, Lung, UTE；fractional ventilation；pulmonary function tests；

Motivation: This study aimed to assess the feasibility of using single breath-hold UTE MRI to quantify pulmonary function and its spatial uniformity in patients with obstructive lung disease.

Goal(s): Comparison of FV in patients with different respiratory stages and correlation with PFTs.

Approach: FV map was obtained from UTE MRI, and IQR of FV was calculated. Group differences of UTE parameters were compared, and correlation between UTE MRI with PFT parameters was assessed.

Results: We found significant differences in whole lung FV and left lung FV among groups, with a positive correlation between FV and PFT parameters such as FEV1 and MMEF.

Impact: This study demonstrates the potential of UTE MRI for assessing pulmonary function in obstructive lung disease patients. By providing regional functional information, UTE MRI might be a useful tool in lung disease management.

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