Abstract #2955

Central Vein Sign and Trigeminal Lesions of Multiple Sclerosis Visualized by 7.0T MRI

Jing Jing¹, Zhe Zhang¹, Lei Su², Yuan Li³, Chenyang Gao², Ai Guo¹, Xinyao Liu¹, Huabing Wang¹, Xinghu Zhang¹, Yaou Liu¹, Emmanuelle Waubant⁴, Fu-Dong Shi¹, and Decai Tian¹

¹Beijing Tiantan Hospital, Beijing, China, ²Tianjin General Hospital, Tianjin, China, ³MR research collaboration team, siemens healthineers, Beijing, China, ⁴Department of Neurology, University of California San Fransisco, San Francisco, CA, United States

Synopsis

Keywords: Multiple Sclerosis, Multiple Sclerosis

Motivation: Multiple sclerosis patients are more vulnerable to trigeminal neuralgia, but the mechanism behind this nerve injury is still unclear.

Goal(s): We aim to investigate trigeminal nerve involvement in MS and provide insight into pathology.

Approach: 120 patients underwent 7.0 T multi-modality MRI scans. T1-MPRAGE, T2-FLAIR, FLAWS-MP2RAGE, and T2*W images were collected.

Results: Our study confirmed the high prevalence of trigeminal nerve on 7.0 T MRI and highlighted the presence of a central vein sign in trigeminal nerve lesions. This study contributes to a deeper understanding of the pathophysiology and location-specific nature of trigeminal lesions.

Impact: This finding reinforces that trigeminal nerve involvement represents a characteristic of MS lesions, which has the potential for precising diagnosis in the future.

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