Keywords: Multiple Sclerosis, Multiple Sclerosis
Motivation: The longitudinal changes of the quantitative MRI parameters in the hippocampus of MS patients and their correlation with clinical factors remains unclear.
Goal(s): This study aimed to characterize the longitudinal changes of quantitative parameters in the hippocampus and explore the relevance of these changes to cognitive assessment.
Approach: Quantitative values calculated using Synthetic MRI technique and extracted for different subregions of the hippocampus.
Results: Compared with healthy controls, significant differences of quantitative values in the hippocampus, particularly in the subiculum, were observed. At 1-year follow-up, clinical improvement was associated with lower T2 values in the entire hippocampus.
Impact: Synthetic MRI can effectively evaluate changes in the normal-appearing hippocampus of MS patients and may be useful for monitoring disease progression clinically.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords