Keywords: Multiple Sclerosis, Neuroinflammation
Motivation: MT-weighted imaging is important for detecting and diagnosing neuro-degenerative disorders. At 7T, high RF power deposition is challenging for MT-weighted sequences and often limits imaging performance.
Goal(s): We demonstrate a high-resolution, MT-weighted, Zero Time Echo (ZTE) sequence which can produce whole-brain images at clinically useful levels of RF power deposition.
Approach: We demonstrate an MT-weighted ZTE sequence for 7T and use it to scan healthy volunteers and subjects with Multiple Sclerosis
Results: Whole-brain MT-weighted ZTE images of high quality and 0.8mm isotropic imaging were produced with clinically useful SAR levels.
Impact: High-resolution MT-weighted ZTE images could provide important novel information for neurologists and psychiatrists.
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