Keywords: Hyperpolarized MR (Non-Gas), Hyperpolarized MR (Non-Gas)
Motivation: Fully sampled 3DspCSI acquisition limits the temporal resolution for dynamic imaging
Goal(s): Our goal was to reconstruct highly under-sampled 3DspCSI without significant image artifacts
Approach: We proposed a low rank plus local sparse (LLS) reconstruction with two types of configurations to reconstruct the under-sampled 3DspCSI data
Results: proposed methods with both types of configurations can effectively reduce the image artifacts due to under-sampling. Type 2 configuration performs slightly better than Type 1 with less image artifacts due to the distinct patterns along the slice dimension
Impact: With the proposed LLS reconstruction, an effective acceleration of 4 can be achieved for 3DspCSI without significant image artifacts. The improvement in temporal resolution helps to quantify the metabolite kinetics during a fixed imaging window with hyperpolarized 13C agents
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