Meeting Banner
Abstract #3048

MRI assessment of skin and muscle sodium (23Na) and fluid volume in haemodialysis patients

Ben Prestwich1, Rebecca Noble2, Kelly White2, Maarten Taal2, Nicholas Selby2, and Susan Francis1,3
1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 2Centre of Kidney Research and Innovation, University of Nottingham, Derby, United Kingdom, 3NIHR Biomedical Research Centre, Nottingham Univ. Hospital NHS Trust and Univ. Nottingham, Nottingham, United Kingdom

Synopsis

Keywords: Non-Proton, Non-Proton

Motivation: To improve understanding of sodium and water balance in haemodialysis patients.

Goal(s): To study sodium stores in leg muscle and skin in younger and older healthy individuals, and haemodialysis patients, and to assess sodium and water changes following a single haemodialysis session.

Approach: Sodium (23Na) MRI of calf skin and muscle in younger older and haemodialysis(HD) patients. 23Na MRI, and 1H mDIXON and T2 relaxometry to study sodium and water content to haemodialysis.

Results: Haemodialysis led to a significant reduction in muscle sodium whilst skin sodium showed little detectable change, 1H muscle T2 values showed a significant reduction.

Impact: Sodium (23Na) MRI of muscle allows the study of sodium storage with age and in dialysis patients. 23Na and proton (1H) T2 mapping enable the assessment of changes in sodium storage and fluid status in haemodialysis patients.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords