Meeting Banner
Abstract #3049

Advancing Brain Tumour Sodium Imaging: Prospectively Accelerated eSISTINA and Compressed Sensing at 7T

Wieland A. Worthoff1, Qingping Chen1,2, Christian Filss1,3, Zaheer Abbas1, Karl-Josef Langen1,3, and N. Jon Shah1,2,4
1Institute of Neurscience and Medicine - 4, Forschungszentrum Juelich GmbH, Juelich, Germany, 2Department of Neurology, RWTH Aachen University, Aachen, Germany, 3Department of Nuclear Medicine, RWTH Aachen University, Aachen, Germany, 4Institute of Neurscience and Medicine - 11, Forschungszentrum Juelich GmbH, Juelich, Germany

Synopsis

Keywords: Non-Proton, Non-Proton, Brain Tumours, Sodium Imaging, Multiple Quantum Filteres, Compressed Sensing

Motivation: Leverage cutting-edge enhanced simultaneous single and triple quantum filtered sodium imaging sodium imaging (eSISTINA) at 7T for unparalleled image precision, enhancing diagnostic efficacy and pushing the clinical frontier in brain tumour analysis.

Goal(s): Optimise imaging and relaxometry performance of the eSISTINA sequence without compromising clinically applicability due to exessive measurement times.

Approach: FLORET spiral trajectories coupled with pseudo-randomised undersampling and compressed sensing reconstruction yield significantly enhanced image quality and relaxometry performance of eSISTINA.

Results: Compressed sensing reconstructed images of a brain tumour patient highlight substantial improvements in quality and aquicistion efficiency of eSISTINA at 7T, surpassing prior work at lower field strengths.

Impact: This study demonstrates clearly that eSISTINA at ultra-high field strength is a promising diagnostic tool, offering invaluable insights for clinicians and researchers. Future patient cohort studies will undoubtedly reveal novel perspectives on brain tumours and metabolism.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords