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Abstract #3101

Radiomics-optimized MRI: Evaluation of keyhole technique to prostate cancer DWI

Rui Jian Chu1, Ivan Jambor2,3, Marko Pesola2,4, Pekka Taimen5, Otto Ettala1, Jani Saunavaara5, Peter Boström1, Hannu Aronen2, and Harri Merisaari2
1Department of Urology, University of Turku, Turku, Finland, 2Department of Diagnostic Radiology, University of Turku, Turku, Finland, 3Radiology Enterprise Service Group, Mass General Brigham, Boston, MA, United States, 4Siemens Healthineers, Helsinki, Finland, 5Department of Medical Physics, Turku University Central Hospital, Turku, Finland

Synopsis

Keywords: Radiomics, Prostate, Repeatability, Optimization

Motivation: Radiomic feature extraction techniques may be combined with reduced k-space data acquisition, if their repeatability and clinical performance would stay in the same levels as with full data acquisition.

Goal(s): We evaluate radiomics for their potential to be used in keyhole imaging acquiring k-space only partially.

Approach: We utilized 78 patients with prostate cancer who underwent short-term test-retest prostate MRI examination. We calculated ADC parameter map with different portions of k-space, simulating keyhole acquisitions. We extracted radiomics, evaluating intra-class correlation coefficient ICC(3,1) changes and area under ROC curve (AUC).

Results: Repeatability and classification performance stayed in acceptable limits for some of the radiomics.

Impact: The technique is relative easy to implement, and thus may benefit clinical MR examinations in the near future.

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Keywords