Keywords: Data Processing, Liver
Motivation: There is a lack of suitable tools for monitoring liver function to determine the optimal treatment strategy for patients.
Goal(s): To evaluate the value of B1-corrected VFA T1 mapping in predicting liver function.
Approach: T1 relaxation time at corresponding time-points in B1-corrected VFA T1 mapping were measured. We analyzed the correlation of T1 value with indocyanine green retention rate at 15min (ICG-R15) and conducted Receiver operating characteristic (ROC) to evaluate the albumin-bilirubin (ALBI) grade classification efficiency by T1 mapping parameters.
Results: T1-10min, T1-HBP and △T1% showed moderate correlation with ICG-R15. T1-5min had the best diagnostic efficacy in differentiating ALBI 1 and ALBI 2.
Impact: This study explored that T1 value of Gd-EOB-DTPA-enhanced MRI by B1-corrected VFA method can be used as noninvasive imaging indicators for estimation of liver function.
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