Keywords: Functional Connectivity, Psychiatric Disorders, subthreshold depression
Motivation: identifying the neural pathology mechanisms has the potential value to elucidate risk factors and prognostic markers for subthreshold depression(StD)
Goal(s): FNC is a useful imaging tool in detecting the neuro-mechanism of the brain
Approach: This study involved in the static functional network connectivity (sFNC) and dynamic functional network connectivity (dFNC) to investigate the FNCdifferences between the StD and HCs groups
Results: StD demonstrated altered FNC in executive control network (ECN), default mode network (DMN), sensorimotor network (SMN) and dorsal attentional network (DAN), in addition, Std had increased mean dwell time and fraction time in a weak connected state concerning the dFNC analysis.
Impact: The sFNC and dFNC findings could enrich our understanding of the large-scale resting-state FNC abnormalities in StD individuals, which could provide insights for a better understanding of the behind neural mechanisms
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