Abstract #3165

Evaluation of Looping Star, a novel silent fMRI technique for auditory task fMRI

Yaoxuan Wang^1,2,3, Yuting Zhu^1,2,3, Shengqi Chen^1,2,3, Yong Zhang⁴, Weiqiang Dou⁴, Mengda Jiang⁵, Xiaofeng Tao⁵, Hao Wu^1,2,3, and Zhaoyan Wang^1,2,3

¹Department of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, ²Ear Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China, ³Shanghai Key Laboratory of Translational Medicine on Ear and Nose Diseases, Shanghai, China, ⁴MR Research, GE Healthcare, Beijing, China, ⁵Department of Radiology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Synopsis

Keywords: Task/Intervention Based fMRI, Neuroscience, Looping Star, silent fMRI, auditory task fMRI, auditory processing

Motivation: The scan noise of Gradient-recalled echo echo-planar imaging (GRE-EPI) is a major confounding factor for auditory task fMRI.

Goal(s): This study evaluated a novel silent fMRI technique, "Looping Star," comparing it to the conventional GRE-EPI method.

Approach: A passive listening task consisting of a continuous stream of multilingual babble was applied for seven participants who underwent Looping Star and GRE-EPI scans respectively using similar scan parameters.

Results: Looping Star showed higher sensitivity in detecting activations in primary auditory areas and additional regions not identified by GRE-EPI.

Impact: The results indicate Looping Star's potential for more accurate and comprehensive auditory task fMRI studies due to reduced acoustic interference.

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