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Abstract #3243

Arbitrary Pulse Sequence Execution with Pulseq on Philips MRI Scanners

Imam Ahmed Shaik1, Qiang Liu1, Ryan Robison2,3, Yansong Zhao4, Maxim Zaitsev5, Jon-Fredrik Nielsen6, Yogesh Rathi1, Carl-Fredrik Westin7, Berkin Bilgic8,9, Borjan Gagoski10, Lipeng Ning1, Andrew Ellison11, Richard J Rushmore12, and William A Grissom13
1Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States, 2Philips, Nashville, TN, United States, 3Vanderbilt University Medical Center, Nashville, TN, United States, 4Philips Healthcare, Cambridge, MA, United States, 5Division of Medical Physics, Department of Radiology, University Medical Center Freiburg, Freiburg, Germany, 6fMRI Laboratory and Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States, 7Department of Radiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States, 8Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 9Department of Radiology, Harvard Medical School, Boston, MA, United States, 10Fetal-Neonatal Neuroimaging and Developmental Science Center, Boston Children’s Hospital, Harvard Medical School, Boston, MA, United States, 11Department of Radiology, Boston University Medical School, Boston, MA, United States, 12Department of Neurobiology, Boston University Medical School, Boston, MA, United States, 13Department of Biomedical Engineering, Case School of Engineering, Case Western Reserve University, Cleveland, OH, United States

Synopsis

Keywords: Data Acquisition, Pulse Sequence Design

Motivation: To enable execution of open-source vendor-agnostic pulse sequences on Philips MRI scanners.

Goal(s): To develop a Pulseq interpreter for Philips scanner.

Approach: An intelligent Philips Pulseq interpreter, denoted "p2p" (Pulseq to Philips), was implemented in MATLAB. It converts Pulseq-generated .seq files into a format compatible with Philips sequence objects.

Results: The p2p interpreter was tested with sequences that included arbitrary gradient waveforms including custom spiral waveforms and crusher waveforms spelling out the words ‘Philips Pulseq’, GRE and DW-EPI scans evaluated in phantoms and in vivo.

Impact: Open-source Pulseq format sequences can be executed with minimal adaptations on Philips scanners. The p2p Pulseq Philips interpreter completes the set of interpreters required to implement harmonized pulse sequences across the three major vendor platforms.

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Keywords