Keywords: Pulse Sequence Design, Pulse Sequence Design
Motivation: Conventional 2D-TSE offers superior tissue contrast compared to 3D-TSE, but its slice thickness is restricted by SNR and slice profile of RF pulse.
Goal(s): Our objective was to achieve 0.4mm isotropic T2-weighted imaging with high contrast and high SNR.
Approach: Amplitude and phase modulated gSlider pulses were developed and incorporated into 2D-TSE. Their performances were evaluated in phantom and in vivo.
Results: The gSlider-TSE achieved 0.4mm isotropic imaging with high accuracy. The SNR was comparable to 8 times averaged conventional 2D-TSE image.
Impact: The gSlider-TSE provides high-resolution isotropic imaging with submillimeter slice thickness and high SNR, while preserving the high contrast of conventional 2D-TSE.
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