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Abstract #3256

gSlider-TSE for high-resolution isotropic T2-weighted imaging with high contrast and high SNR

Jinyuan Zhang1,2,3, Yue Wu1,2,3, Rong Xue1,2,3, Yan Zhuo1,2,3, and Zihao Zhang1,2,4
1State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, 2University of Chinese Academy of Sciences, Beijing, China, 3The Innovation Center of Excellence on Brain Science, Chinese Academy of Sciences, Beijing, China, 4Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China

Synopsis

Keywords: Pulse Sequence Design, Pulse Sequence Design

Motivation: Conventional 2D-TSE offers superior tissue contrast compared to 3D-TSE, but its slice thickness is restricted by SNR and slice profile of RF pulse.

Goal(s): Our objective was to achieve 0.4mm isotropic T2-weighted imaging with high contrast and high SNR.

Approach: Amplitude and phase modulated gSlider pulses were developed and incorporated into 2D-TSE. Their performances were evaluated in phantom and in vivo.

Results: The gSlider-TSE achieved 0.4mm isotropic imaging with high accuracy. The SNR was comparable to 8 times averaged conventional 2D-TSE image.

Impact: The gSlider-TSE provides high-resolution isotropic imaging with submillimeter slice thickness and high SNR, while preserving the high contrast of conventional 2D-TSE.

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