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Abstract #3257

Technical Advances of T1 Relaxation-Enhanced Steady-State (T1RESS) Sequences with Radial Acquisition for Contrast-Enhanced Examination

Ruoxun Zi1,2,3, Robert R Edelman4, Christoph Maier1,2, Mahesh Bharath Keerthivasan5, Riccardo Lattanzi1,2, and Kai Tobias Block1,2
1The Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 3Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, United States, 4Radiology, Northshore University HealthSystem, Evanston, IL, United States, 5Siemens Medical Solutions, New York, NY, United States

Synopsis

Keywords: Pulse Sequence Design, Tumor, Stack-of-stars Acquisition

Motivation: Sequences from the T1RESS family offer increased lesion conspicuity in contrast-enhanced brain examinations. Recently, radial variants have been developed to improve motion robustness.

Goal(s): To enable broader clinical utilization of radial T1RESS sequences.

Approach: Dynamic imaging is enabled through combination with GRASP reconstruction. Fat/water separation is achieved by integrating the multi-echo Dixon technique. Further scan acceleration is achieved by applying 1D GRAPPA along the kz dimension.

Results: The proposed extensions are demonstrated for brain imaging at 3T in volunteers and patients, revealing dynamic lesion-enhancement patterns, successful fat/water separation, and supplementary scan acceleration with comparable quality and lesion conspicuity.

Impact: The proposed technical extensions of radial stack-of-stars T1RESS sequences, including dynamic reconstruction, fat/water separation, and parallel imaging, will enable broader clinical utilization of this novel sequence family and may result in noticeably improved sensitivity for lesion detection throughout the body.

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Keywords