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Abstract #3284

Super Resolution Using Sparse Sampling at Portable Ultra-Low Field MR

Corinne Donnay1,2, Serhat V Okar3, Megan Poorman4, Daniel S Reich3, and Govind Nair5
1NINDS, NIH/Oxford, Bethesda, MD, United States, 2Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, United Kingdom, 3NINDS, NIH, Bethesda, MD, United States, 4Hyperfine Inc, Guilford, CT, United States, 5NIH, Bethesda, MD, United States

Synopsis

Keywords: New Trajectories & Spatial Encoding Methods, Low-Field MRI, Super Resolution

Motivation: Ultra-low field (ULF) MRI is cost-effective and portable but has limited signal-to-noise ratio (SNR) and lower resolution.

Goal(s): To develop a Fourier-based Super Resolution (FouSR) approach to enhance the resolution of ULF MRI images by combining spatial frequencies from two orthogonal ULF images.

Approach: In a standard phantom and a cohort of 10 participants with multiple sclerosis (MS) we compared FouSR to ULF coronal and axial images and their average.

Results: FouSR demonstrated improved image sharpness and lesion delineation without sacrificing SNR. Visual assessments of in-vivo data by an experienced MS neurologist supported the superior image quality of FouSR.

Impact: The presented Fourier-based Super Resolution (FouSR) approach improves image resolution of ultra-low field MRI, providing sharper images for radiological assessment.

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