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Abstract #3301

Zoomed imaging with calibration-free destructive B1+ shimming for rapid fMRI

Emma J P Brouwer1,2, Wietske van der Zwaag1,2, and Nikos Priovoulos1,2,3
1Spinoza Centre for Neuroimaging, Royal Netherlands Academy of Arts and Sciences, Amsterdam, Netherlands, 2Computational Cognitive Neuroscience and Neuroimaging, Netherlands Institute for Neuroscience, Amsterdam, Netherlands, 3Biomedical Engineering and Physics, MS Center Amsterdam UMC location VUmc, Amsterdam, Netherlands

Synopsis

Keywords: fMRI Acquisition, fMRI, B1-shim

Motivation: High-resolution MRI enables precise studies of specific brain regions but this comes at a cost of increased acquisition time.

Goal(s): We examined if calibration-free destructive interferences can be introduced with simple static B1-shims for zoomed fMRI acquisitions.

Approach: We optimised destructive B1 phase offsets and implemented these whilst assessing image quality in MPRAGE, tSNR in an EPI timeseries, flip angle distributions and |B1|.

Results: Calibration-free destructive shims allowed reducing the field-of-view (50%) and acquisition-time (35%), while retaining good signal (higher B1 and similar tSNR) in the target (visual cortex).

Impact: The calibration-free destructive B1 shims can be applied across brain regions with standard head coils and therefore translate across neuroscientific studies, while reducing acquisition-time and signal contributions from noise-prone areas. This may flexibly improve the spatial resolution and signal quality.

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Keywords