Keywords: Functional Connectivity, Brain
Motivation: The biophysical mechanisms underlying changes in functional connectivity upon stroke remain unclear.
Goal(s): The present study aims at investigating how disrupting a specific and well-localized cortical area modulates spontaneous long-range functional connectivity.
Approach: A novel approach based on intrinsic oscillatory modes exhibiting stationary wave pattern features was used to provide insight into the organizing principles underpinning spontaneous long-range FC.
Results: The presented intrinsic mode framework revealed global reorganization following local disruption with enhancement of corticostriatal activity in stroke.
Impact: Our findings provide an important insight augur well for better understanding of neural network reorganization.
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