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Abstract #3331

The relationship between preoperative PI-RADS version 2.1 and Gleason score change after radical prostatectomy

Jiahui Zhang1, Lili Xu2, Zhengyu Jin2, and Hao Sun2
1Department of Radiology, Peking Union Medical College Hospital, Beijing, China, 2Peking Union Medical College Hospital, Beijing, China

Synopsis

Keywords: Prostate, Cancer

Motivation: If reliable preoperative risk factors to predict Gleason score (GS) upgrading after radical prostatectomy (RP) are identified, such could be helpful to reduce the risk of misclassification of PCa patients.

Goal(s): To investigate the relationship between Prostate Imaging Reporting and Data System version 2.1 (PI-RADS v2.1) and GS change after RP.

Approach: Multivariate analyses were performed to analyse the factors influencing GS change after RP.

Results: Multivariate regression analysis showed positive biopsy cores of ≥ 4, biopsy Gleason score of <7 and PI-RADS v2.1 score of 4–5 were independent predictors of GS upgrading after RP (all P < 0.05).

Impact: Combining the number of positive biopsy cores, biopsy Gleason score and PI-RADS v2.1 score could significantly improve the diagnostic efficiency for Gleason score upgrading after radical prostatectomy.

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