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Abstract #3338

Accelerated MR Fingerprinting with 1 mm3 spatial resolution for prostate cancer at 3.0 T

Jesus Ernesto Fajardo Freites1, Jiayao Yang2, Tejinder Kaur1, Nicole Seiberlich3, Vikas Gulani1, and Yun Jiang1,4
1Department of Radiology, University of Michigan, Ann Arbor, MI, United States, 2Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, United States, 3Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States, 4Department of Biomedical Engineering, Univeristy of Michigan, Ann Arbor, MI, United States

Synopsis

Keywords: Prostate, Prostate, prostate cancer, 3D MRF Fingerprinting

Motivation: MRF has shown to have potential to separate cancer from non-cancer in the prostate. Improving resolution and accuracy of tissue property maps while lowering acquisition times could expedite clinical adoption of this technique.

Goal(s): To obtain high-resolution 3D T1 and T2 maps in the prostate in a single rapid scan.

Approach: A highly undersampled isotropic 1 mm3 SoS MRF FISP sequence with B1+ and B0 correction was developed.

Results: We obtained high-resolution 3D T1 and T2 maps of the prostate from a single 6-minute scan and report these values in the normal-appearing prostate from 6 subjects and a PIRADS 5 suspected lesion.

Impact: High-resolution quantitative 3D T1 and T2 maps using a single 6-minute scan may enable this technology to be used for detection and characterization of prostate lesions and encourage clinical adoption.

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