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Abstract #3346

Correlation Between Morphological Measurements of Intra- and Extracranial Vessel Wall and Whole-Body Fat Distribution Characteristics

Hong Zhang1,2, XuanLe Li2, Yue Xu1, Chuanli Cheng2,3, Yingtong Wu2, Jiangjun Qin1, Ye Li2,3,4, Dong Liang2,3,4, Xin Liu2,3,4, Hairong Zheng2,3,4, and Na Zhang2,3,4
1Sanya Central Hosptial(Hainan Third People's Hospital), sanya, China, 2Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, shenzhen, China, 3United Imaging Research Institute of Innovative Medical Equipment, shenzhen, China, 4Key Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, shenzhen, China

Synopsis

Keywords: Vessel Wall, Data Analysis, Vessel Wall Morphological Measurements; Whole-Body Fat Distribution

Motivation: Obesity is associated with cardiovascular diseases. However, its effect on cerebrovascular disease remains unclear.

Goal(s): To investigate the correlation between morphological measurements of intra- and extracranial arterial vessel walls and whole-body fat distribution characteristics.

Approach: A total of 98 volunteers underwent three-dimensional high-resolution MR vessel wall imaging and whole-body MR proton density fat fraction (PDFF) imaging on a 3.0T MRI scanner.

Results: The results indicate that the vessel wall thickness of both the extracranial carotid artery and vertebral artery is positively correlated with visceral adipose tissue and the liver-PDFF.

Impact: The assessment of vascular health in individuals with central obesity necessitates a comprehensive evaluation of both extracranial carotid arteries and vertebral arteries. This paradigm shift may have far-reaching implications for the prevention and treatment of cerebrovascular diseases associated with obesity.

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Keywords