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Abstract #3363

3D phase contrast MRI of the coronary arteries – Improvements and adaptations at 3T

Denise Lichthardt1, Jens Wetzl2, Michaela Schmidt2, Peter Speier2, Christoph Tillmanns3, Armin M. Nagel1, and Daniel Giese2
1Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, 2Siemens Healthineers AG, Erlangen, Germany, 3Diagnostikum Berlin, Berlin, Germany

Synopsis

Keywords: Flow, Motion Correction

Motivation: 3D Phase contrast MRI of the coronary arteries remains challenging due to low SNR and motion.

Goal(s): Develop a 3D PC sequence for flow quantification in the coronary arteries at 3T with improved SNR and reduced motion artefacts compared to 1.5T.

Approach: The sequence was optimized by acquiring datasets separately, enabling inter-scan motion compensation while circumventing SAR limitations. Coronary flow was quantified in 5 subjects at 3T.

Results: Phantom measurements showed reduced image artefacts using the proposed sequence. In-vivo mean peak velocities per slice along the left and right coronary arteries were 15.9±5.0cm/s and 14.1±4.9cm/s respectively.

Impact: High SNR 3D flow measurements in the proximal coronary arteries are now possible, as SAR restrictions at 3T have been overcome. This may enable the non-invasive hemodynamic assessment of coronary arteries in patients with CAD.

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