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Abstract #3381

Feasibility of a 2D Radial Simultaneous Multi-Slice Phase Contrast MRI sequence for Aortic Pulse Wave Velocity Measurements

Tarun Naren1, Grant S Roberts1, Kevin M Johnson1,2, Bri Breidenbach3, Mackenzie Jarchow3, Sarah Lose3, Alyssa Pandos3, Ozioma Okonkwo3, and Oliver Wieben1,2
1Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 2Radiology, University of Wisconsin-Madison, Madison, WI, United States, 3Medicine, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Flow, Velocity & Flow, Simultaneous Multi-Slice, Pulse Wave Velocity

Motivation: Pulse wave velocity (PWV) is an important biomarker for cardiovascular risk that can be measured non-invasively with phase contrast MRI. Sequential scans at different planes can lead to inaccurate measurements so an alternate approach is needed.

Goal(s): We aim to develop a 2D simultaneous multi-slice (SMS) radial phase contrast sequence to image multiple planes concurrently, reduce timing inconsistencies, and measure PWV more accurately.

Approach: The radial phase contrast SMS sequence was implemented on a GE scanner and included in an ongoing volunteer study.

Results: The SMS scan provided higher quality images in less scan time than sequential and had reduced timing inconsistencies.

Impact: Pulse wave velocity (PWV) is a clinically important biomarker for cardiovascular risk. A simultaneous multi-slice radial 2DPC sequence allows for faster, more accurate MR flow measurements with high temporal resolution and reduced timing inconsistency which can improve early detection.

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Keywords