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Abstract #3383

Monitoring relative diameter change of the carotid artery using non-contrast-enhanced 4D dynamic angiography: preliminary results

Isabel Montón Quesada1, Augustin C. Ogier1, Robin Ferincz1, Jean-Baptiste Ledoux1,2, Aurélien Bustin1,3,4, Patrik Michel5, Jérôme Yerly1,2, Matthias Stuber1,2, Christopher W. Roy1, and Ruud B. van Heeswijk1
1Department of Radiology, Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2CIBM Center for BioMedical Imaging, Lausanne, Switzerland, 3IHU LIRYC, Electrophysiology and Heart Modeling Institute, INSERM U1045, Centre de recherche Cardio-Thoracique de Bordeaux, Université de Bordeaux, Bordeaux, France, 4Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux, France, 5Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland

Synopsis

Keywords: Vascular, Blood vessels, Carotid Diameter, Pulsatile Motion, Angiography

Motivation: The carotid artery anatomy is routinely studied with MRI, whilst its relative diameter change is evaluated using ultrasound. An MRI technique to measure the carotid diameter change throughout the cardiac cycle could therefore be complementary to the existing toolset.

Goal(s): To combine carotid MR angiography and diameter change quantification in one scan without contrast agent injection.

Approach: A 4D (3D+time) free-running sequence was extended with slab-selective RF pulses to increase the inflow blood-to-muscle contrast. Carotid diameter changes and contrast ratios were quantified.

Results: The contrast ratio significantly improved with the use of slab-selective pulses and the carotid relative diameter change was precisely measured.

Impact: 4D free-running MR angiography with slab-selective RF pulses allows for the dynamic visualization of the carotid lumen and the quantification of the relative carotid diameter change throughout the cardiac cycle without contrast agent injection.

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Abstract

Keywords