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Abstract #3388

Automatic Carotid Plaque Segmentation Using Deep Learning Model with Multi-Head Loss Integrating Anatomical Features

Long Yang1, Jinhua Dong2, Xiong Yang2, Yufei Mao2, Guanxun Cheng3, Ye Li1,4,5, Dong Liang1,4,5, Xin Liu1,4,5, Hairong Zheng1,4,5, and Na Zhang1,4,5
1Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shen Zhen, China, 2Department of Image Advanced Analysis of HSW BU, Shanghai United Imaging Healthcare Co., Ltd., Shanghai, China, 3Department of Radiology, Peking University Shenzhen Hospital, Shenzhen, China, 4Key Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, Shenzhen, China, 5United Imaging Research Institute of Innovative Medical Equipment, Shenzhen, China

Synopsis

Keywords: Vessel Wall, Stroke

Motivation: With the assistance of prior vessel wall mask, segmentation of atherosclerotic plaque can achieve satisfactory performance. However, manual sketching of vessel wall mask is still time-consuming.

Goal(s): To propose a method for fast and accurate plaque segmentation without relying on prior knowledge of vessel walls.

Approach: This study proposes a deep learning model based on a multi-head loss design for automatic segmentation of carotid artery plaques, with the aim of reducing dependence on prior information of vessel walls in plaque segmentation.

Results: In the independent test, the model with the multi-head loss design achieving excellent results similar to using vessel wall prior.

Impact: This study achieved fully automatic and accurate plaque segmentation without manual priors, which will greatly reduce burden of radiologist to segment and quantify plaque, and also contribute to more efficient stroke risk assessment, progress monitoring, and efficacy evaluation for patient.

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