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Abstract #3391

CMR-based estimation of mean pulmonary arterial pressure and pulmonary vascular resistance in CTD-PAH

Kefan Ma1, Yidan Zhu1, Wangyan Liu1, Xiaomei Zhu1, Qiang Wang2, Xiaoxuan Sun2, Yinsu Zhu3, and Yi Xu1
1Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 2Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 3Department of Radiology, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, China

Synopsis

Keywords: Vascular, Cardiovascular

Motivation: This research explores the potential of cardiac magnetic resonance (CMR) as a noninvasive tool for evaluating pulmonary arterial hypertension (PAH) in connective tissue disease-associated PAH (CTD-PAH) patients.

Goal(s): The goal is to estimate mean pulmonary arterial pressure (mPAP) and pulmonary vascular resistance (PVR) accurately using CMR metrics, with right heart catheterization (RHC) as the gold standard.

Approach: Correlations between CMR and RHC parameters were assessed, and predictive models for mPAP and PVR were developed.

Results: Strong correlations were observed between RHC and CMR metrics. Predictive CMR models were established for both mPAP and PVR, offering potential clinical applications.

Impact: CMR parameters can be used to estimate mPAP and PVR in patients with CTD-PAH, potentially providing a noninvasive method for assessing pulmonary arterial hemodynamics during CTD-PAH management.

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