Abstract #3399

Anatomy of neo-aorta can cause abnormal flow patterns

Dominik Daniel Gabbert¹, Lucas Langnaese², Michael Neidlin³, Alois Schaffarczyk⁴, and Inga Voges²

¹Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein, Kiel, Germany, ²Department of Congenital Heart Disease and Pediatric Cardiology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany, ³Dept. of Cardiovascular Engineering Institute of Applied Medical Engineering, Institute of Applied Medical Engineering, RWTH Aachen University, Aachen, Germany, ⁴Faculty of Mechanical Engineering, University of Applied Sciences Kiel, Kiel, Germany

Synopsis

Keywords: Flow, Surgery, Congenital heart disease

Motivation: The descending aorta (DAo) in patients with hypoplastic left heart syndrome (HLHS) after Norwood procedure is frequently enlarged although this region is not subject to surgical procedures.

Goal(s): The aim of this study is to investigate whether the aortic anatomy can cause abnormal flow patterns which are related to vascular alterations.

Approach: Based on anatomic models and flow boundaries from 4D flow MRI, we studied fluid-dynamics using CFD simulations.

Results: We found increased vorticity and wall-shear stress in the HLHS descending aorta. Increased wall shear stress has been associated with the development of dilation and may explain vascular alterations in the descending aorta.

Impact: This study gives motivation for further investigations and may ultimately lead to future Norwood procedure modifications.

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