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Abstract #3438

Dual-FOV MB-SWIFT for simultaneous functional imaging of the brain and spinal cord

Lin WU1, Sara Ponticorvo1, Hanne Laakso2, Ekaterina Paasonen2, Jaakko Paasonen2, Mikko Kettunen2, Russell Lagore1, Lance DeLabarre1, Gregor Adriany1, Dee Koski1, Michael Garwood1, Djaudat Idiyatullin1, Olli Gröhn2, Silvia Mangia1, and Shalom Michaeli1
1Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, United States, 2A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland

Synopsis

Keywords: Functional Connectivity, fMRI, dual FOV

Motivation: Functional neuroimaging target either the brain or the spinal cord, but usually not both because simultaneous acquisitions from distant fields of view are challenging with conventional MRI.

Goal(s): To establish a novel MRI approach for artefact-free, quiet fMRI simultaneously from brain and spinal cord, avoiding the need of dynamic shimming.

Approach: Our approach is to use MB-SWIFT in a simultaneous dual-FOV configuration with a Dual Amplifier Blanking Selector Unit (DABSU) that employs two transmitters and two receiver channels.

Results: The results established feasibility of the novel approach for task-based fMRI and connectivity analyses between lumbar spinal cord and brain in rat.

Impact: The method could be used for unprecedented investigations of the central nervous system, and could be extended to any two separate parts of the body.

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