Keywords: Myocardium, Myocardium, SLE
Motivation: Early detection of myocardial injury in Systemic lupus erythematosus (SLE) patients is important.
Goal(s): Find a clinical biomarker for preclinical myocardial injury in SLE patients.
Approach: CMR-FT (Cardiac Magnetic Resonance Feature Tracking) technology and CVI 42 software were used to measure cardiac functional parameters and myocardial strain parameters for SLE patients with/without subclinical myocardial injury and healthy controls.
Results: Compared to the control group, the circumferential strain (CS) and longitudinal strain (LS) were found to be reduced in patients with subclinical myocardial injury in SLE. The CMR-FT technology was able to detect changes in myocardial strain before a decrease in ejection fraction occurred.
Impact: Early detection of myocardial injury in SLE patients and proactive treatment are important for improving patient outcomes. This study found that CMR-FT quantitative technique can identify subclinical myocardial damage in patients with SLE.
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