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Abstract #3540

Hemodynamics and vessel morphology in Fontan patients at a high-altitude surgical center

Carson Platnick1, Hannah Spears1, Samuel Schofield1,2, Nicolas Drysdale1, Benjamin Frank1,2, Matthew Stone1,2, Michael DiMaria3, Jennifer Romanowicz 1,2, Jenny Zablah1,2, Gareth Morgan1,2, Joseph Kay1, Vitaly O. Kheyfets1,2, Brian Fonseca1,2, Lorna P. Browne1,2, and Mehdi H. Moghari1,4
1University of Colorado, Aurora, CO, United States, 2Children's Hospital Colorado, Aurora, CO, United States, 3University of Michigan, Ann Arbor, MI, United States, 4Children's Hospital Colorado, Denver, CO, United States

Synopsis

Keywords: Flow, Vessels

Motivation: There is currently limited data examining longitudinal changes in hemodynamics and vascular properties in Fontan patients living at altitude.

Goal(s): We aimed to assess hemodynamic parameters and vessel morphology in Fontan patients at a single high-altitude surgical center and assess correlations between these parameters and post-Fontan outcomes.

Approach: We retrospectively reviewed patients undergoing Fontan operation from 1999 to 2021. We analyzed data from cardiac magnetic resonance imaging and cardiac catheterization.

Results: Our findings highlight post-Fontan changes in flow, pressure, and area. The changes in systemic and caval flow, along with pressure variations, offer insights into the effects of Fontan circulation.

Impact: This study advances our understanding of Fontan circulation at high-altitude, paving the way for improved prognostic information and long-term outcomes in this patient population.

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Keywords