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Abstract #3561

Partial Diffusion-weighted MR Fingerprinting for the simultaneous quantification of relaxation time and diffusion coefficient

Yiang Wang1, Elaine Y.P. Lee1, and Peng Cao1
1Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, China

Synopsis

Keywords: MR Fingerprinting, Image Reconstruction

Motivation: Subspace reconstruction has the potential to generate high-resolution images from highly undersampled data at each time point.

Goal(s): To develop an MRF-based approach to simultaneously measure relaxation time and diffusion coefficient.

Approach: This sequence was composed of two parts: conventional MRF and DW-SSFP. The central k-space was fully sampled, and the peripheral k-space was under sampled with 24 interleaves, using a dual density spiral trajectory. The subspace reconstruction was applied using the temporal basis obtained from central k-space data.

Results: T1, T2, PD, and ADC can be accurately quantified for both phantom and in-vivo scans.

Impact: This work indicate that full-resolution DWI can be reconstructed at each time point for a multi-shot multi-dynamic sequence using the subspace reconstruction. Our proposed sequence can be used to estimate relaxation time, proton density and diffusion coefficient simultaneously.

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Keywords