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Abstract #3573

Creation of Voxelwise 2D Lookup Tables (LUTs) for MRF-based Synthesis of Qualitative Images

Andrew Dupuis1, Yong Chen2, Mark A Griswold1,2, and Rasim Boyacioglu2
1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 2Radiology, School of Medicine, Case Western Reserve University, Cleveland, OH, United States

Synopsis

Keywords: MR Fingerprinting, Visualization

Motivation: Address the challenge of integrating MRF data into existing MRI analysis via synthetic images without introducing spatial artifacts or hallucinations possible with CNNs.

Goal(s): Generate static lookup tables (LUTs) mapping from T1/T2 value space directly to grayscale visualizations matching clinical contrasts.

Approach: A simple pixel-wise regression network was trained on a public dataset of MRF data and weighted images. Static LUTs were generated from dictionaries of T1/T2 combinations, then applied to MRF-derived maps for visualization and processing via FSL.

Results: Successful generation of synthetic contrast LUTs ensures reproducibility and allows instantaneous visualization or registration of MRF maps in a more conventional grayscale format.

Impact: Integration of MRF into traditional analysis pipelines suffers because quantitative maps have inherently different contrasts from weighted images. LUTs for instant, deterministic generation of weighted contrasts from T1/T2 maps allow for direct use of tools like FSL with MRF data.

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Keywords