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Abstract #3622

Few-shot Learning for Differentiation of Malignant and Benign Breast Cancer Lesions Using Dynamic Contrast-enhanced MRI

Fatemeh Zabihollahy1,2, Renata Pinto1,2,3, Masoom A. Haider1,2, and Vivianne Freitas2
1Lunenfeld-Tanenbaum Research Institute, Sinai Health System, University of Toronto, Toronto, ON, Canada, 2Joint Department of Medical Imaging, University Health Network, Sinai Health System and Women’s College Hospital University of Toronto, Toronto, ON, Canada, 3Radiology Department, Instituto Nacional do Cancer (INCa), Rio de Janeiro, Brazil, Rio de Janiro, Brazil

Synopsis

Keywords: Diagnosis/Prediction, Breast

Motivation: Breast cancer (BrCa) is the most prevalent malignancy among women. MRI is a useful tool for BrCa early detection and characterization. However, high false-positive rates can lead to unnecessary biopsies and patient distress. To enhance diagnostic accuracy, deep learning presents a promising avenue, but training deep neural networks (DNN) requires a large, annotated dataset.

Goal(s): Introduce a novel method for BrCa classification, utilizing a minimally labeled dataset.

Approach: We employ a few-shot learning (FSL) approach to differentiate between benign and malignant breast tumors.

Results: Our FSL-based model significantly surpasses the diagnostic performance of trained radiologists in breast cancer classification (p < 0.0001).

Impact: Our FSL model streamlines machine learning by reducing data labeling needs outperforms radiologists in detecting breast cancer, and could reduce unnecessary biopsies, sparing patients from potential harm.

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