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Abstract #3657

Synthetic derivative T2-weighted abdominal images from T1-weighted images using a generative adversarial network (GAN)

Shu Zhang1, Phillip Martin2,3, Nakul Gupta1, Maria Altbach3,4, Ali Bilgin2,3,4, and Diego Martin1
1Radiology, Houston Methodist Research Institute, Houston, TX, United States, 2Electrical and Computer Engineering, University of Arizona, Tucson, AZ, United States, 3Medical Imaging, University of Arizona, Tucson, AZ, United States, 4Biomedical Engineering, University of Arizona, Tucson, AZ, United States

Synopsis

Keywords: Liver, Multi-Contrast, Image-to-image translation

Motivation: Either fast 2D T2-weighted abdominal imaging or 3D T2 MIP techniques have limitations. There remains a need for fast 3D T2 abdominal high-resolution imaging.

Goal(s): To develop a conditional GAN model to synthesize T2-weighted images from 3D high-resolution T1-weighted abdominal images preserving spatial resolution of the source images.

Approach: Abdominal images acquired from 39 volunteers were included for the study. A conditional GAN model was trained to generate T2-weighted images from T1-weighted images slice by slice.

Results: Overall, the generated T2-weighted images were similar to the real T2-weighted images, though some contrast differences in the bowels and kidneys were seen.

Impact: This proof of principle study shows the GAN model can be used to generate T2-weighted images from T1-weighted images, with the potential for rendering high quality volumetric 3D high-resolution abdominal T2-weighted images that is superior to current 3D MIP methods.

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Keywords