(ISMRM 2024) An Automatically Optimised Gaussian Weighting Function Width for Magnitude-Weighted Phase-Based Electrical Properties Tomography (EPT)
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Abstract #3682

An Automatically Optimised Gaussian Weighting Function Width for Magnitude-Weighted Phase-Based Electrical Properties Tomography (EPT)

Jierong Luo1, Oriana Arsenov1, and Karin Shmueli1
1Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom

Synopsis

Keywords: Electromagnetic Tissue Properties, Electromagnetic Tissue Properties, MR-EPT, electrical conductivity mapping, electrical properties tomography, noise reduction

Motivation: Phase-based electrical properties tomography calculates conductivities by fitting the transceive phase weighted by a Gaussian function of the magnitude image with width δ. Currently, δ is selected empirically and its impact on conductivities is unknown.

Goal(s): To investigate the effect of δ on conductivity maps and develop a method to automatically select δ.

Approach: After evaluating relationships between δ and healthy brain conductivities at 3T, we calculated conductivities using a voxel-wise δ based on inverse phase noise and compared the results.

Results: Increasing δ decreased contrast and noise in conductivity maps. Our new method to calculate a varying δ automatically optimised conductivity maps.

Impact: We have developed a method to calculate a varying Gaussian weighting width for EPT. This will enable automatic optimisation of conductivity maps rather than time-consuming empirical choice of δ, facilitating the use of phase-based EPT and broadening its applicability.

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Keywords

conductivitydeltamagnitudetissueconductivitiesmapsnoisebrainslice