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Abstract #3703

MRI and tumor-infiltrating CD8+ T cell-based nomogram for predicting meningioma recurrence risk stratification

Tao Han1, Xianwang Liu1, and Junlin Zhou1
1Lanzhou University Second Hospital, Lanzhou, China

Synopsis

Keywords: Tumors (Pre-Treatment), Tumor

Motivation: To investigate the efficacy of MRI features and CD8+ T cells in predicting risk stratification for meningioma recurrence.

Goal(s): To develop a reliable nomogram incorporating MRI features and CD8+ T cells to predict meningioma recurrence.

Approach: Conventional MRI features, ADC histogram parameters, and CD8+ T cells were recorded and compared. This model was the first to combine clinical, imaging, and TME data to predict meningioma recurrence.

Results: The ADCp1 and CD8+ T cells as predictive variables for meningioma recurrence and patients with low ADCp1 or CD8+ T cell counts had higher recurrence rates than those with high ADCp1 or CD8+ T cell counts.

Impact: The findings will improve prognostic accuracy for patients with meningioma and potentially allow for targeted treatment of individuals who have the recurrent form.

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