Keywords: Quantitative Imaging, Relaxometry, Phase-Based T2 mapping, T2* (star) mapping
Motivation: To provide strategies for accurate, and high-fidelity quantitative T2 and T2* quantitative imaging.
Goal(s): To study the feasibility of simultaneous quantification of T2 and T2* using gradient-echo readouts at 3T.
Approach: We employed a multi-GRE-based acquisition with optimized TR and RF phase increments to estimate T2 and T2* maps from the acquired phase and magnitude images, respectively. We demonstrated the accuracy and feasibility of our methods, both in the ISMRM/NIST phantom and in vivo.
Results: Phase-based T2 mapping method can be combined with T2* mapping while increasing the accuracy of the T2 estimation.
Impact: This work shows that it is feasible quantify simultaneously T2 and T2* using a single multi-echo GRE acquisition.
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