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Abstract #3753

Synthetic MRI to evaluate myometrial invasion and predict pathologic type of endometrial cancer: compared with high-resolution T2WI and DWI

Yue Li1, Yigang Pei2, Hui Liu2, Weiyin Vivian Liu3, Yijing Luo2, Yu Bai2, Xiaorong Ou2, and Wenzheng Li2
1Radiology, Department of Radiology, Xiangya Hospital, Central South University, Changsha, China, 2Department of Radiology,Xiangya Hospital, Central South University, Changsha, China, 3GE Healthcare,MR, Beijing, China

Synopsis

Keywords: Synthetic MR, Cancer

Motivation: Depth of myometrial invasion (DMI), lymphovascular invasion (LI) and pathological types of endometrial cancer (EC) affect decision-making on an optimal treatment plan for uterus.

Goal(s): This study aimed to investigate the feasibility of MAGIC in evaluating the DMI and predicting the pathological types of EC.

Approach: The assessment performance of MAGIC in comparison to hr-T2WI on DMI and prediction of EC types in comparison to ADC were performed.

Results: T2 and PD together had a superior predictive performance to ADC only, and sy-T2WI showed the similar assessment performance on DMI to hr-T2WI.

Impact: One more application of MAGIC-generated contrast images and quantitative parameter maps in cervical diagnosis may provide additional information on diagnosis of DMI and classification of pathological types of EC.

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