Keywords: Synthetic MR, Brain, Acquisition Methods, Challenges, High-Field MRI MR, Fingerprinting/Synthetic MR, MR Value, Multiple Sclerosis, Neuro, Parallel Transmit & Multiband, Relaxometry
Motivation: Redefining MP2RAGE sequence for clinical efficiency.
Goal(s): To provide a time-efficient MP2RAGE parameterization with on-demand synthetic T1-weighted contrasts.
Approach: Sequence parameters are chosen to minimize idle time while maximizing CNRWM/GM. Synthetic contrasts are derived from T1 map. Experimental validation is carried for 7T brain imaging using plug-and-play parallel transmission.
Results: Time-efficient MP2RAGE reduced acquisition time by up to 40% compared to reference, while maintaining contrast quality. Multiple sclerosis patients benefited from enhanced lesion visualization with a 10min, (0.67mm)3 time-efficient protocol. This optimization enabled shorter acquisition times or higher resolution within a given time budget, while providing an exhaustive set of brain T1-w contrasts.
Impact: A time-efficient MP2RAGE sequence parameterization is proposed, resulting in faster, higher-resolution 3D T1-weighted brain imaging compared to conventional settings, combined with a complete set of synthetic T1-w contrasts generated online, with meaningful potential in clinical and research practice.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords