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Abstract #3762

Synthesizing multiple realistic MR phase images using a multi-modal generative model

Nikhil Deveshwar1,2, Abhejit Rajagopal1, Michael Lustig2, and Peder E.Z. Larson1
1Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, United States

Synopsis

Keywords: Synthetic MR, Machine Learning/Artificial Intelligence

Motivation: Deep learning MRI reconstruction methods face challenges in available datasets to train models. Clinical scans can be a source for diverse data but a challenge is obtaining MRI phase.

Goal(s): We propose a method to generate multiple plausible synthetic phase images from a single magnitude-only input.

Approach: We train a multi-modal generative model enforcing consistency in the latent space during training. We evaluate the effect of latent vector dimension on diversity and quality of the synthetic images with FID score and training image reconstruction models with this synthetic data.

Results: Higher latent vector dimension resulted in more diverse and higher quality synthetic images.

Impact: This method could be used to generate multiple plausible phase images from a single scan to model effects of varying field homogeneity, RF coils, echo time, motion, flow, and susceptibility

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Keywords