Keywords: Quantitative Imaging, Multi-Contrast
Motivation: Multi-contrast quantitative MRI usually requires multiple scans, leading to long acquisition time and potential inter-scan misalignment.
Goal(s): To achieve the multi-contrast quantitative MRI acquisition in a single scan and improve the accuracy of the quantitative mapping.
Approach: We developed a multi-contrast quantitative mapping sequence to simultaneously obtain T1, T2, T2* maps and subvoxel QSM. Reconstruction was conducted to directly estimate the underlying quantitative maps from the highly undersampled high-dimensional k-space data. The proposed framework was validated on the simulation, phantom and healthy volunteers.
Results: The results demonstrated that our proposed method exhibited a high correlation with references on the quantitative maps.
Impact: The proposed acquisition and reconstruction framework can simultaneously provide multi-contrast quantitative maps of the whole brain within a 5.8-minute scan. This new technique is clinically promising for tissue characterization and pathological research in neurosciences.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords