Keywords: Tumors (Pre-Treatment), Tumor, MULTI-parametric MR imaging with fLEXible design（MULTIPLEX）; contrast-enhanced(CE); gradient recalled-echo(GRE);brain tumor; intracranial metastasis
Motivation: Early monitoring for intracranial metastatic lesions through non-invasive methods will directly impact patient prognosis and quality of life.
Goal(s): The aim of this study was to evaluate the performance of MULTIPLEX in detecting brain metastases.
Approach: Signal-to-noise ratios (SNRs) for gray matter (GM) and white matter (WM), contrast-to-noise ratios (CNRs) for lesion/GM, lesion/WM, and GM/WM were quantitatively compared.
Results: MULTIPLEX aT1 imaging is preferred for depicting lesions containing hemorrhage or calcifications.
Impact: The combination of MULTIPLEX T1 and aT1 sequences enhances the detection of brain metastatic lesions compared to T1-GRE imaging, which could be helpful for detecting of small metastatic tumors.
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