Keywords: Tumors (Pre-Treatment), Tumor, Diffusion; Pituitary adenoma
Motivation: Preoperative evaluation of the consistency of pituitary adenomas (PAs) plays a significant role in the surgical strategy. However, previous studies concerning the assessment of tumor consistency of PAs were controversial1-4.
Goal(s): To evaluate the ability of the continuous-time random-walk (CTRW) diffusion model to predict the consistency and extent of resection (EOR) of PAs.
Approach: The CTRW diffusion model relaxes a priori distributions of waiting times and distance increments of water molecular diffusion, providing a realistic description of the complex structures of biological tissues5.
Results: CTRW diffusion model could provide information about the tumor consistency and EOR of PAs.
Impact: CTRW diffusion model provides an imaging dimension for characterizing tissue microstructure of PAs and may serve as a promising tool to predict the tumor consistency and EOR in patients with PAs.
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