(ISMRM 2024) A continuous-time random-walk diffusion model for predicting tumor consistency and extent of resection in patients with pituitary adenomas
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Abstract #3848

A continuous-time random-walk diffusion model for predicting tumor consistency and extent of resection in patients with pituitary adenomas

Chun-Qiu Su1, Zeng-Ping Lin2, Ran Tang2, Ke Xue2, Hai-Bin Shi1, and Shan-Shan Lu1
1Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 2United Imaging Healthcare, Shanghai, China

Synopsis

Keywords: Tumors (Pre-Treatment), Tumor, Diffusion; Pituitary adenoma

Motivation: Preoperative evaluation of the consistency of pituitary adenomas (PAs) plays a significant role in the surgical strategy. However, previous studies concerning the assessment of tumor consistency of PAs were controversial1-4.

Goal(s): To evaluate the ability of the continuous-time random-walk (CTRW) diffusion model to predict the consistency and extent of resection (EOR) of PAs.

Approach: The CTRW diffusion model relaxes a priori distributions of waiting times and distance increments of water molecular diffusion, providing a realistic description of the complex structures of biological tissues5.

Results: CTRW diffusion model could provide information about the tumor consistency and EOR of PAs.

Impact: CTRW diffusion model provides an imaging dimension for characterizing tissue microstructure of PAs and may serve as a promising tool to predict the tumor consistency and EOR in patients with PAs.

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Keywords

diffusion