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Abstract #3916

Improved characterization of sequence-specific peripheral nerve stimulation (PNS) thresholds for rapid on-scanner monitoring

Mathias Davids1,2, Natalie Ferris1,3,4, Valerie Klein1,2, Alex Barksdale1,5, Bastien Guerin1,2, and Lawrence Wald1,2,4
1Martinos Center, Massachusetts General Hospital, Charlestown, MA, United States, 2Harvard Medical School, Boston, MA, United States, 3Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA, United States, 4Harvard-MIT Division of Health Sciences and Technology, Boston, MA, United States, 5MIT Department of Electrical Engineering and Computer Science, Cambridge, MA, United States

Synopsis

Keywords: Bioeffects & Magnetic Fields, Safety, Peripheral Nerve Stimulation (PNS), gradient coils, fast imaging

Motivation: The on-scanner PNS monitor must estimate each sequence’s stimulation potential. The current SAFE model is overly conservative, unnecessarily restricting gradient performance by up to 1.8X.

Goal(s): Develop a PNS monitor model that rapidly and accurately characterizes a sequence’s PNS thresholds.

Approach: We propose a model (SAFE2) closely inspired by the mechanisms of PNS to capture critical aspects such as E-field cancelations from different gradient axes and extend the training data using detailed PNS modeling reflecting a more diverse set of waveforms.

Results: SAFE2 improves PNS-prediction accuracy by 2X compared to SAFE, boosting usable image encoding performance by up to 30% without hardware changes.

Impact: PNS restricts the usable protocol parameters of EPI, bSSFP, Radial-GRE, etc., yielding suboptimal imaging performance. The current PNS monitoring approach (SAFE) is very conservative, therefore, we propose an improved model yielding up to 30% gradient performance boost without hardware modification.

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Keywords